General Introduction-Introduction to Metal ions in biology,
Biological ligands, terminology (amino acids, polypeptide, proteins, enzymes, how to name enzymes, DNA and RNA)
Zinc containing Metalloenzymes, CA
Zinc containing Metalloenzymes CP, ADH
Zinc containing Metalloenzymes phosphatase (alkaline and acid), nuclease and phospholipase.
Electron transfer protein; Fe-S, Cu and Heme
Redox enzyme: Cu-Zn SOD, Introduction to Peroxidase
Redox enzyme: Peroxidase, Catalase and introduction to cytochrome P450
Redox enzyme: Cytochrome P450, Xanthine Oxidase, Introduction to Splitting of water
Redox enzyme: Splitting of water, Nitrogen fixation.
Vitamin B12 co-enzyme; Introduction to O2 transport protein; Hematin formation
Structure of Hemoglobin, myoglobin, Pauling and Weiss theory,
Cooperative effect, Bohr effect, Methemoglobin, toxicity due to CO
Toxicity due to CN, Methemoglobin, Hemocyanin
Hemoerythrin-summary of oxygen transport proteins. Introduction to metals in medicine
Cisplatin, synthesis, mechanism of action and SAR Ru, Au complexes for cancer therapy.
Chelation therapy and Metallothionenes. Antiviral drugs